Thus, the photodamage leads to permanent photoaging that is characterized by collagen deficiency, collagenase excess and micro and macrocicatrices Night Comfort Review.At the histological level it has also been shown that the skin with chronic photodamage presents increased fragmented collagen , decrease in procollagen and growth of the collagenase arm.
The intrinsic aging, on the contrary, is characterized because it is a non-scarring continuous process where over time the skin becomes thin, fragile and the wrinkles are fine.
It is believed that over the years the accumulation of free radicals also leads to increased collagenase and decreased collagen formation (Night Comfort Review).
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